Explain how mutated bacteria are able to resist fluoroquinolones?

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03-10-2020
Biology

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Explain how mutated bacteria are able to resist fluoroquinolones?

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mpg1244 mpg1244 · Answer 1 · 2020-10-03T06:44:58+02:00

mpg1244 mpg1244

03-10-2020

i think the answer is: The dominant mechanisms of fluoroquinolone resistance identified are 1) chromosomal mutations causing reduced affinity of DNA gyrase and topoisomerase IV for fluoroquinolones and 2) overexpression of endogenous MDR pumps.

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